Every output of a pipeline is a shadow of an organism nobody can observe directly. This book is about how we license claims about it.
Every chapter has the same anatomy: a live controversy · the philosophical tools that sharpen it · a small simulation · a Monday-morning rule · open problems.
An open book: Challenge a claim, add a case, or propose a counterexample through issue templates. Each chapter reviewed by a philosopher of science and a practitioner, to be named.